Dept. of Microbiology
Icahn School of Medicine at Mount Sinai
New York, NY
Dr. Dusan Bogunovic obtained his PhD at NYU School of Medicine, NY, NY, USA in Molecular Oncology and Immunology. During my PhD training, he examined examined the function of Toll-Like Receptor (TLR) agonists on dendritic cells and the role of immune system in advanced melanoma. He delineated the pathways involved in observed suppression of inflammation when the two TLRs were co-ligated, and demonstrated the functional relevance of this finding in T cell lineage commitment. Subsequently, his postdoctoral training took place at the Rockefeller University, NY, NY, USA where he discovered null mutations in ISG15 in patients who suffered from mycobacterial disease and had persistent Type I IFN inflammation. He showed essential roles for both free extracellular and free intracellular ISG15. In 2014, He accepted a tenure-track Assistant Professor position in the Microbiology Department of the Icahn School of Medicine at Mount Sinai. The Bogunovic lab focuses on the study of human immunogenetics, dissecting pathways negatively regulating inflammation, and defining the role for ISGylation in humans. Dusan has been co-chair of the ICIS Membership & Communications Committee since 2017.