The International Society for Interferon and Cytokine Research (ISICR) is a non-profit organization of scientists devoted to research in the fields of interferon, cytokine and chemokine cell biology, molecular biology, biochemistry and the clinical use of these biological response modifiers. Each year the ISICR sponsors an international meeting where scientists can present their latest findings to the worldwide scientific community. Membership in the society is open to all individuals interested in interferons, cytokines and chemokines. For more information about the ISICR or how to join the ISICR, please go to www.isicr.org.
Charles Samuel is the C. A. Storke II Professor. He earned a B.S. in Chemistry from Montana State and his Ph.D. in Biochemistry from U.C. Berkeley. He was a Damon Runyon Scholar at Duke Univ. Med. Sch. where he began work on interferon. At UCSB he served as Director of the Interdepartmental Biochemistry & Molecular Biology Program (BMSE) from 1987-95, as Founding Chair of the Department of Molecular, Cellular & Developmental Biology from 1995-98, and again as MCDB Chair from 2001-04. He is an NIH Research Career Development Awardee, an NIH MERIT awardee, a FASEB Wellcome Professorship awardee, a Humboldt Forschungspreis recipient, and an elected Fellow of the American Association for the Advancement of Science and the American Academy of Microbiology. He is an Associate Editor of the Journal of Biological Chemistry, and serves on the editorial boards of Virology, Journal of Virology, and Journal of Interferon and Cytokine Research.
The overall objective of the research in The Samuel Lab is to elucidate in molecular terms the mechanisms by which interferons exert their antiviral and cell growth control actions in mammalian cells. Present work includes biochemical and molecular genetic studies of two interferon-inducible enzymes, PKR and ADAR. PKR is a double-stranded RNA-dependent protein kinase induced by IFN, and activated by RNA-dependent autophosphorylation. PKR plays a major role in the regulation of translation of viral and cellular mRNAs and also modulates transcription and signaling. The ADAR1 deaminase is an RNA editing-enzyme that catalyzes the C-6 deamination of adenosine to yield inosine, thereby altering the genetic decoding and structure of RNAs. While PKR displays antiviral and proapoptic activities, ADAR1 is often proviral and antiapoptotic in virus-infected cells. Furthermore, PKR is not required for normal mouse embryogenesis, whereas ADAR1 is required.
Thomas Alan Hamilton, Ph.D., is a Professor in the Department of Molecular Medicine at Cleveland Clinic Lerner College of Medicine, at Case Western Reserve University. He has held this position since 2003. In addition, he is a Professor with the Department of Molecular Virology, Immunology and Medical Genetics, Ohio State University School of Medicine. Dr. Hamilton also has held positions at many prestigious institutions, including Stanford University, St. Jude Children’s Research Hospital and Duke University Medical Center.
His clinical research interests include: Regulation of Inducible Gene Expression in Mononuclear Phagocytes, Regulation of Chemoattractant Cytokine Expression in Tissue Inflammation and Chemokine Function. His research has been published in leading peer-reviewed journals and he has contributed chapters to medical textbooks in his field. He has been the editor-in-chief, Journal of Interferon and Cytokine Research since 2002. In addition, Dr. Hamilton is an international speaker and presenter.
In 1971, Dr. Hamilton received his BA in Biology/Chemistry at the University of Colorado. He went on to earn his Ph.D. in Biochemistry in 1976 at University of Oregon Health Sciences Center, in Portland. Dr. Hamilton completed several fellowships during this time, including a National Institutes of Health pre-doctoral fellowship in Biochemistry at University of Oregon Health Sciences Center, in Portland, Oregon, and also a NRSA-postdoctoral traineeship in tumor biology, Department of Pathology at Stanford University Medical School, Stanford, California (1976-1978).
Dr. Hamilton is a member of numerous professional associations, including the American Association of Immunologists (Chair, Program Block on NK cells and Macrophages 1996-1999); American Association for Advancement of Science; Society for Leukocyte Biology (Nominating Committee – 1991, Councilor 1992 – 1995, Treasurer 1995-1998; President Elect – 1998; President – 1999; International Society for IFN Research; Secretary 2006-2009); and the International Cytokine Society, among others.
Dr. Friedman currently serves as the chairman of the Department of Pathology for the Uniformed Services University of the Health Sciences in Bethesda, MD. He has held this position since 1981 after serving in many different capacities at the National Institutes of Health. Dr. Friedman earned his M.D. from New York University College of Medicine, attending after achieving a New York State Medical Scholarship.
Among the numerous societies of which he is a member, Dr, Friedman also belongs to the American Association of Immunologists, the American Society for Microbiology, and the American Society for Experimental Pathology. He has achieved recognition in many areas, including representative for the Joint Japan-American Conference on Interferon 1970, member of the editorial board for the Journal of Virology and president of the International Society for Interferon and Cytokine Research in 2003. He also served from time to time as a visiting lecturer at several universities and research institutes, and as a book reviewer or ad hoc editorial consultant for several professional journals. His research interests include pathology, virology, immunology, and oncology.
Lisa Hetherington joined FASEB in 2007 as Senior Project Coordinator in the managed Society Services department. With over 10 years of administrative and management experience, Lisa is responsible for coordinating and implementing activities for several client societies.
Before coming to FASEB, Lisa served as Director and Manager for various operational, research and publication services. From 2005 to 2007, as the manager of a business analyst group, she planned, directed and coordinated system development life cycles for support and implementation of software changes.
From 1998 to 2005, Lisa worked for a privately owned direct mail firm, serving in different capacities as a Client Service Manager for fulfillment and publishing clients and as the Warehouse Operations Director, managing over $7 million of client inventory.